Top 20 Best Isekai Anime with OP MC

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Subhra Jit


Most Isekai series don’t shy away from boasting about their overpowered protagonists. The main character of many of the series is infinitely powerful, so much so, that lifting a finger might defeat an opponent. But in hindsight, people love this genre because of its excessively powerful main characters.

So again, we are diving into the divergent world of sword and sorcery to find out the top 10 Isekai anime with overpowered main characters of all time.

These main characters have the ability to almost destroy a city in the blink of an eye. They are top of the top in the Isekai genre as the strongest. Here is a list of the Top 10 Isekai Anime With An Overpowered Main Character.

So, without any further ado let’s jump in!

20. In Another World With My Smartphone

In Another World With My Smartphone is a charming anime which follows its main character, a man named, Touya, as he is mistakenly killed. To make amends for this, god allows him to reincarnate in another world with his smartphone. In his new life, he finds that the world is filled with magic and supernatural creatures. Unsurprisingly, our main character is also supremely talented in these areas and paired with the power of technology, there are hardly any situations he can’t get out of. The series is a standard Isekai tale which sticks to what it knows best. It has a beautiful female cast which makes up the main character’s harem and is an enjoyable experience overall.

19. Tsukimichi: Moonlit Fantasy

Tsukimichi: Moonlit Fantasy for the underdog anime of its season which managed to surpass all expectations. It follows a young boy named Makoto who is scheduled to be reincarnated into another world. However, the god in charge decided that he was too hideous and pushed him to the farthest corner of the world away from human civilization. While initially having contempt for the god, Makoto soon realizes that he has an affinity for magic and is able to interact with the supernatural creatures in this world. Using these to his advantage, he recruits several allies who join him on his journey across the world. They overcome several obstacles by working together and deepening their bond. The series has delightful animation and a very likeable cast of characters who only elevate it.

18. How to Not Summon a Demon Lord

Many people enjoy watching Isekai animes for their stupidly powerful protagonists who manage to woe every girl he meets. This holds true more than ever for How to Not Summon a Demon Lord. The series follows a gamer named Takuma who plays as the Demon King Diablo in a game. His life changes when he ends up being summoned to another world as his game character. In this world, he is greeted by two beautiful girls who wished to capture him but failed in doing so. While being forced to work under him, they experience several adventures and even have hilarious coincidences together which contributed to the Ecchi element of the series. How to Not Summon a Demon Lord is a fantastic guilty pleasure anime with a powerful and comedic main character surrounded by pretty females. While the story isn’t its strongest aspect, it is still very satisfying to watch.

17. Seirei Gensouki

Also known as Spirit Chronicles, Serei Gensouki starts by introducing us to a college student who dies in an accident and reincarnates as a young boy named Rio in another world. While he was born in questionable surroundings, he was able to wield magical powers. Using these, he manages to save the kidnapped princesses of the kingdom and gets granted the means to join the Royal Academy. While Rio was excited to join, he soon finds several obstacles in his way and those of higher birth constantly looking down on him. However, with the few meaningful connections he made, he persists and grows in strength while defeating everyone in his way. In addition to watching the development of the main character, the anime has a great female cast that makes up his harem and push him to become stronger.

16. Isekai Cheat Magician

Right from its name, fans know that they can expect extremely overpowered main characters who always keep surprising their enemies with their strength in Isekai Cheat Magician. The anime revolves around a boy and girl named Taichi and Rin as they are suddenly dragged out of their normal lives and reincarnated in a fantastical world with magic and other supernatural elements. While they soon run into trouble against a beast which threatens them, the pair are saved by adventurers who warn them to stay armed. However, we soon find out that they are not going to have too many struggles in this world as their magical powers surpass most others and they are so called “Cheat Magicians”. Together, they work towards understanding the reason behind their transportation while facing any hurdles that come along the way.

15. Farming Life in Another World

Farming Life in Another World is unlike any other anime on this list as it deals with a main character who is overpowered in his profession of farming rather than fighting others. It follows a man named Hiraku who has a very unfortunate life. Due to this, he is allowed to reincarnate into another world with an all-powerful tool which helps him in anything related to farming. Using this, he makes the most of his new life as he cultivates land and gradually keeps adding elements till it becomes an impressive society. With its calm atmosphere, it is an amazing slice of life series with elements of fantasy and is a perfect comfort watch for fans.

14. Saga of Tanya the Evil

Saga of Tanya the Evil is an exhilarating series which revolves around a badass and brutal female protagonist. We are introduced to our protagonist, a man who challenged God and ended up being reincarnated as a little girl as punishment. To make matters worse, the girl is dropped into a world of war and magic. However, with the hatred in her heart of being placed in this situation and wishing to enact vengeance upon God, she mercilessly moves forward while becoming a warrior feared by both the enemy and her own army. With clever strategies and her own unparalleled strength, she brings despair to everyone who stands in her way while growing the Empire she serves. Saga of Tanya the Evil is an epic story which has plenty of hype moments that give the viewer chills. The main character might seem weak, but she is one of the most overpowered in anime and makes the series a must-watch.

13. The Eminence in Shadow

The Eminence in Shadow is a breakout hit which has impressed fans everywhere with its hilarious comedy and extremely unique and powerful main character. It follows a man named Cid who always wished to become strong and solve his problems from the shadows. While his human body restricted him from doing so and eventually led to his demise from an accident, he ends up reincarnating in a world of magic. In this life, he is able to achieve all his dreams as he becomes powerful beyond belief and sets up a secret organization which acts in the shadows. The plot of the anime is very charming and gripping while having a lot of electrifying moments that make us even bigger fans of Cid.

12. No Game No Life

Based on the popular novel, No Game No Life tells the story of a brother and sister named Sora and Shiro as they are transported to a fantasy world. In this world, everything is dominated by games and any issue is solved by playing them. Being geniuses in this department who dedicated most of their time to playing games, Sora and Shiro instantly take a liking to their new environment and decide to defeat everyone until they become the rulers. No Game No Life has extremely colourful animation, exhilarating battles and comedic scenes to balance it out and is a very enjoyable anime.

11. The Misfit of Demon King Academy

One of the strongest, most ruthless and coolest protagonists fans can find in anime is without a doubt Anos Voldigoad. As the king of demons, he had previously sacrificed himself to end a war with humanity and ends up being born again in the future. To his surprise, however, he finds several events of history to be altered in this future. With his strength and knowledge, he decides to set the world in the right track while showcasing the greatness of the demon king. The series is extremely engaging as we watch Anos destroy all who oppose him without a sweat. Therefore, The Misfit of Demon King Academy is one anime that everyone needs to watch.

10. The Devil is a Part-Timer

Sadao Maou from The Devil is a Part-Timer
  • AUTHOR: Satoshi Wagahara
  • EPISODES: 13
 A very unexpected plot for Isekai. Who has ever thought a Demon lord can also get teleported to Earth? A story of a demon lord working part-time in McDonald’s. A very fun and engaging story with a lot of serious plot twists. But don’t worry our MC is very overpowered as he is the Demon Lord.


 If you feel the ends justify the means, how does that make you different from us demons, exactly?

Sadao Maou

The Devil King once declared war on Ente Isla in an attempt to annex the four continents. But the hero and her companions forced him to retreat inside Earth. Here he becomes weak as magic does not exist in this world. Soon he becomes a part-timer at McDonald’s to earn money and rule Earth. By the way, you may think he is not overpowered. But he is too much power as you will see throughout the series. Because he did not need to power up like other characters, he was from the beginning the strongest.

9. The World’s Finest Assassin Gets Reincarnated in Another World as an Aristocrat

Lugh Tuatha Dé from The World's Finest Assassin Gets Reincarnated in Another World as an Aristocrat
  • AUTHOR: Rui Tsukiyo
  • EPISODES: 12

An Isekai story depicting the strongest assassin on earth who gets reincarnated. The plot of this story is too dark and the main character also matches the circumstances very well. What will happen if the Goddess asks you to assassinate the hero in your new world? The awesome and intriguing path of Lugh.


I’ve killed people. I’m going to continue killing a lot of people. That’s the mission that’s been handed to me.

– Lugh Tuatha Dé

The protagonist Lugh might be the strongest assassin of all in Isekai history. Lugh is the designated heir of the House of Tuatha Dé. Tuatha Dé being the house of assassins, Lugh was taught in both the arts of medicine and assassination by his father.

In his previous life, Lugh was the strongest assassin on Earth but was betrayed by his people. He was given a second chance at life but there was a twist. Lugh is tasked with the job of killing the Hero, who will eventually destroy the world. The overpowered hero must be killed by our strongest assassin or there might very well be no future for that world.

8. CAUTIOUS HERO: The Hero is Overpowered but Overly Cautious

Seiya Ryuuguuin from Cautious Hero
  • AUTHOR: Light Tuchihi
  • EPISODES: 12

Gaeabrande a world that is ruled by Demon Lord has to be saved by the goddess Ristarte. She chose our main character Seiya for this job and summons him. He is very strong from the beginning and also trains from every god to get even stronger. But he has a problem which is his cautiousness.

MAIN CHARACTER: Ryuuguin Seiya

Be careful. Be cautious. Be overly cautious. You may find yourself alienated or hated, but you have to endure it all. This time, for sure, you’ll prove that you can save your friends, your loved ones, and the entire world.

– Ryuuguin Seiya


A  protagonist who even the gods fear. Seiya upon coming to save the S-class world Gaeabrande tries everything to become strong. Because of his cautiousness, he seldom takes part in fights. But he trains ruthlessly to get even stronger every moment. Even some gods were defeated by him and his enthusiasm for training.

Though Seiya tries to ignore fights, when it comes to fighting even the Demon lord is not a match for him. Take part in the hilarious journey of Ryuuguin Seiya and Ristarte and discover the unlimited powers of our main character.

7. Arifureta: From Commonplace to World’s Strongest

Nagumo Hajime from arifureta from commonplace to worlds strongest
  • AUTHOR: Ryo Shirakome
  • EPISODES: 12 + 2 OVAs (Season 2 Ongoing)

A dark Isekai with the plot of revenge and also a protagonist who kills their enemies mercilessly. As an Isekai fan, what more do you want? Still, it’s not all for the story, our main character also has the power to oppose and kill the gods by himself. With the ambition of returning home, he kills ruthlessly everywhere he went. 


“I don’t care if we used to be classmates. I won’t hesitate to kill you.”

– Nagumo Hajime

Unlike typical Isekai a whole group of students was transported to another world. But our main character was the weakest with the ability of synergists. After being insulted, ridiculed, and humiliated for his lack of powers, he gets betrayed by a classmate. He was thrown into the darkest hell of a labyrinth.

There using his brain and his ability he kills monsters and eats them. But after eating them he was mutated into a human-monster hybrid. After clearing the labyrinth he became stronger and came to realize his true enemies. Now he has the power to kill gods. Hajime Nagumo is massively overpowered and he doesn’t hold back when he sees his enemies, destroying them from organ to organ.

6. Wise Man’s Grandchild

Shin Wolford from Wise Man’s Grandchild
  • AUTHOR: Tsuyoshi Yoshioka
  • EPISODES: 12

This beautiful Isekai is a top-tier series if we compare it based on an overpowered main character and awesome action scenes. The main character is truly overpowered to the point where his grandpa Merlin also looks timid about his power. Merlin was originally the strongest mage in that world. And also this series covers a beautiful romance plot with our MC.


Hunting demons may be the work of justice, but when you hunt girls too, you become villains.         

– Shin Wolford

The overpowered main character Shin Wolford is the adopted grandchild of the most powerful magician in the verse, Merlin Wolford. Shin was a young office worker who suddenly died in a car accident and was reincarnated in the new magical world of sword and sorcery. He swiftly learns all the teachings from his grandpa and becomes overpowered.

The knowledge of science from his previous life helped him in his magical journey as he sets to revolutionize magical tools. He is also capable of performing magical spells without words. Soon in this story, he almost breaks all the past scales of power level becoming almost the strongest.

5. The Rising of The Shield Hero

Naofumi Iwatani from The Rising Of The Shield Hero
  • AUTHOR: Aneko Yusagi
  • EPISODES: 25

If you love dark plots with overpowered Heroes you might like this. The circumstances for the protagonist from the beginning were hard. After being betrayed by everyone from a nation he decides to get stronger for sweet revenge. Do you think spears, swords, or bows are strong weapons? Your belief might get destroyed in this series as our MC is an OP shield user.

MAIN CHARACTER: Iwatani Naofumi 

I’ve gained more important things thanks to becoming the shield hero. Wherever the waves go I’ll go with my friends.

– Naofumi Iwatani


 Iwatani Naofumi, an easy-going Japanese student gets teleported to a parallel world along with 3 cardinal heroes. After being teleported to the other world he was betrayed by his party member and was also exiled out of the kingdom.

In the new world unbeknownst to the dangers, Naofumi loses all hope from his life. But soon after he forms a party with a demi-human Raphtalia and starts his journey. After forming his own party with Filo and Raphtalis he gets a reason to get stronger. He decides to protect them and save the world from any possible danger.

4. Mushoku Tensei: Jobless Reincarnation

Mushoku Tensei: Jobless Reincarnation
  • AUTHOR: Rifujin no Magonote
  • EPISODES: 23

A series that shows the life of a sad and hopeless person getting another chance at his pitiful life. This anime’s most eye-catching point is its world-building which the author has done very realistically. But throughout the series we see the main character getting stronger as he faces different difficult situations. As we travel through this world we came to know the power scaling which is significantly different than other Isekai. If you like a slow build-up plot for power-up you will love it.

MAIN CHARACTER: Rudeus Greyrat

“It’s no good to overestimate me. Victory is something that you grasp by always being modest, you know.”

– Rudeus Greyrat

An unnamed 34-year-old NEET who dies in a car accident wakes up in another world as a baby. He remembers everything from his past life even the traumas he went through. From birth, Rudeus is overpowered as he has the mental capacity of a 34-year-old man.

As time passes he started training under his father and a magician Roxy. Eventually, he gets better at both but as a magician, he reaches already a different level than others even crossing his teacher. Follow Rudeus and see how he protects the people he loves with his powers.

3. Soul Land(Douluo Dalu)

Tang San from Soul Land
  • AUTHOR: Tand Jia San Shao
  • EPISODES: 191 (Ongoing)

A Chinese anime series that comes in 3rd place on our list. Soul Land is an awesome series with beautiful world development and an awesome plotline. Our main character, who becomes overpowered as the story progresses, also takes part in some heart-wrenching fight sequences. This series is truly an underrated series when it comes to Isekai. If you haven’t watched it you must watch it soon. 


“Because you’re my father. My life was given by you. Without you, how would there be me? Children never have the right to blame their parents.”

– Tang San

Tang San, the most brilliant student of the Tang Sect, is a prodigy when it comes to martial arts and hidden weapons. But because of some incidents, he commits suicide and re-opens his eyes to the beautiful world of Soul Land. In this world, he learns soul power is everything. But he was born with the weakest combat spirit.

However, this doesn’t stop our protagonist in any way, as he begins his journey to be the greatest spiritual master of events. As he also remembered his memories he quickly jumps levels and becomes very strong. As the story hasn’t ended yet he is still getting stronger. But when it comes to the ability he is one in a million and also can defeat many opponents above his level.

Soul land is available on Youtube for free

2. Overlord

 Momonga from Overlord
  • AUTHOR: Kugane Maruyama
  • EPISODES: 39

What will the strongest character of a game do if he gets transported into the game itself? This anime focuses on the feelings of a being with unlimited powers. If you are a fan of a protagonist who has a dark side to himself and kills ruthlessly this series might be your cup of tea. The series is making a comeback with a movie and its 4th season this year.

MAIN CHARACTER: Ainz Ooal Gown(Momonga)

“Death by the sword. Death by broken bones. Death by crushing. There’s not much difference, right? You die at the end.”

– Ainz Ooal Gown

Ainz is the main protagonist and the leader of the guild Ainz Ooal Gown. He is also the Overlord of the Great Tomb of Nazarick and also the creator of Pandora’s Actor. The strongest of the 41 supreme beings of the game, Ainz-Sama has now teleported to E-Rantel, a city that looks like the game he used to play. The strong, mighty, and ruthless Ainz also has a soft side for the guardians and NPCs of Nazarick. 

Read More:
Best Isekai of All Time that You must Watch

1. That Time I Got Reincarnated as a Slime

Rimuru Tempest from That Time I Got Reincarnated as a Slime
  • AUTHOR: Fuse
  • EPISODES: 48 + 5 OVAs

A power fantasy series carrying one of the most overpowered main characters of Isekai. The most popular anime protagonist of 2019(by Crunchyroll), Rimuru is the strongest character on our list. But the surprise is that not only our MC is OP but also he created some monsters which are stronger than any normal OP MC.  If you still haven’t watched this series, watch it quickly or you will miss our little slime’s rampage on another world. 

MAIN CHARACTER: Rimuru Tempest

“To everyone who went against us, we will bare our fangs and retaliate. To everyone who lends their hands to us, we will grant our blessing to them. To our opponents, we will do to them what they have done to us. In the future, I hope that we can be linked in a friendship one day.” 

– Rimuru Tempest

Mikami Satoru after being stabbed to death gets reincarnated into another world as a Slime. In this new world, he meets the storm dragon Veldora and befriends him. He receives a name from him which is Rimuru Tempest. He has a unique ability called Predator. Predator gives Rimuru the power of the entities that he eats. He also later in the series becomes a Demon Lord. If you are an Isekai fan and like awesome action, this might be your perfect anime to watch.


Isekai Anime With An Overpowered Main Character

Now with that, we have come to the end of our list of the top 10 Isekai Anime with overpowered main characters!

Have you watched all of these anime? If you haven’t what are you waiting for? Comment below if you like our content and tell us which one is your favorite OP MC from our list.

Thanks a ton for reading thus far!

See ya!

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Subhrajit is a university student who loves to watch anime and read manga. He has been watching anime for a long time. Now he has decided to write and share his love for anime with others.
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