Top 10 Best Isekai Anime with OP MC

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Subhra Jit


Most Isekai series don’t shy away from boasting about their overpowered protagonists. The main character of many of the series is infinitely powerful, so much so, that lifting a finger might defeat an opponent. But in hindsight, people love this genre because of its excessively powerful main characters.

So again, we are diving into the divergent world of sword and sorcery to find out the top 10 Isekai anime with overpowered main characters of all time.

These main characters have the ability to almost destroy a city in the blink of an eye. They are top of the top in the Isekai genre as the strongest. Here is a list of the Top 10 Isekai Anime With An Overpowered Main Character.

So, without any further ado let’s jump in!

10. The Devil is a Part-Timer

Sadao Maou from The Devil is a Part-Timer
  • AUTHOR: Satoshi Wagahara
  • EPISODES: 13
 A very unexpected plot for Isekai. Who has ever thought a Demon lord can also get teleported to Earth? A story of a demon lord working part-time in McDonald’s. A very fun and engaging story with a lot of serious plot twists. But don’t worry our MC is very overpowered as he is the Demon Lord.


 If you feel the ends justify the means, how does that make you different from us demons, exactly?

Sadao Maou

The Devil King once declared war on Ente Isla in an attempt to annex the four continents. But the hero and her companions forced him to retreat inside Earth. Here he becomes weak as magic does not exist in this world. Soon he becomes a part-timer at McDonald’s to earn money and rule Earth. By the way, you may think he is not overpowered. But he is too much power as you will see throughout the series. Because he did not need to power up like other characters, he was from the beginning the strongest.

9. The World’s Finest Assassin Gets Reincarnated in Another World as an Aristocrat

Lugh Tuatha Dé from The World's Finest Assassin Gets Reincarnated in Another World as an Aristocrat
  • AUTHOR: Rui Tsukiyo
  • EPISODES: 12

An Isekai story depicting the strongest assassin on earth who gets reincarnated. The plot of this story is too dark and the main character also matches the circumstances very well. What will happen if the Goddess asks you to assassinate the hero in your new world? The awesome and intriguing path of Lugh.


I’ve killed people. I’m going to continue killing a lot of people. That’s the mission that’s been handed to me.

– Lugh Tuatha Dé

The protagonist Lugh might be the strongest assassin of all in Isekai history. Lugh is the designated heir of the House of Tuatha Dé. Tuatha Dé being the house of assassins, Lugh was taught in both the arts of medicine and assassination by his father.

In his previous life, Lugh was the strongest assassin on Earth but was betrayed by his people. He was given a second chance at life but there was a twist. Lugh is tasked with the job of killing the Hero, who will eventually destroy the world. The overpowered hero must be killed by our strongest assassin or there might very well be no future for that world.

8. CAUTIOUS HERO: The Hero is Overpowered but Overly Cautious

Seiya Ryuuguuin from Cautious Hero
  • AUTHOR: Light Tuchihi
  • EPISODES: 12

Gaeabrande a world that is ruled by Demon Lord has to be saved by the goddess Ristarte. She chose our main character Seiya for this job and summons him. He is very strong from the beginning and also trains from every god to get even stronger. But he has a problem which is his cautiousness.

MAIN CHARACTER: Ryuuguin Seiya

Be careful. Be cautious. Be overly cautious. You may find yourself alienated or hated, but you have to endure it all. This time, for sure, you’ll prove that you can save your friends, your loved ones, and the entire world.

– Ryuuguin Seiya


A  protagonist who even the gods fear. Seiya upon coming to save the S-class world Gaeabrande tries everything to become strong. Because of his cautiousness, he seldom takes part in fights. But he trains ruthlessly to get even stronger every moment. Even some gods were defeated by him and his enthusiasm for training.

Though Seiya tries to ignore fights, when it comes to fighting even the Demon lord is not a match for him. Take part in the hilarious journey of Ryuuguin Seiya and Ristarte and discover the unlimited powers of our main character.

7. Arifureta: From Commonplace to World’s Strongest

Nagumo Hajime from arifureta from commonplace to worlds strongest
  • AUTHOR: Ryo Shirakome
  • EPISODES: 12 + 2 OVAs (Season 2 Ongoing)

A dark Isekai with the plot of revenge and also a protagonist who kills their enemies mercilessly. As an Isekai fan, what more do you want? Still, it’s not all for the story, our main character also has the power to oppose and kill the gods by himself. With the ambition of returning home, he kills ruthlessly everywhere he went. 


“I don’t care if we used to be classmates. I won’t hesitate to kill you.”

– Nagumo Hajime

Unlike typical Isekai a whole group of students was transported to another world. But our main character was the weakest with the ability of synergists. After being insulted, ridiculed, and humiliated for his lack of powers, he gets betrayed by a classmate. He was thrown into the darkest hell of a labyrinth.

There using his brain and his ability he kills monsters and eats them. But after eating them he was mutated into a human-monster hybrid. After clearing the labyrinth he became stronger and came to realize his true enemies. Now he has the power to kill gods. Hajime Nagumo is massively overpowered and he doesn’t hold back when he sees his enemies, destroying them from organ to organ.

6.  Wise Man’s Grandchild

Shin Wolford from Wise Man’s Grandchild
  • AUTHOR: Tsuyoshi Yoshioka
  • EPISODES: 12

This beautiful Isekai is a top-tier series if we compare it based on an overpowered main character and awesome action scenes. The main character is truly overpowered to the point where his grandpa Merlin also looks timid about his power. Merlin was originally the strongest mage in that world. And also this series covers a beautiful romance plot with our MC.


Hunting demons may be the work of justice, but when you hunt girls too, you become villains.         

– Shin Wolford

The overpowered main character Shin Wolford is the adopted grandchild of the most powerful magician in the verse, Merlin Wolford. Shin was a young office worker who suddenly died in a car accident and was reincarnated in the new magical world of sword and sorcery. He swiftly learns all the teachings from his grandpa and becomes overpowered.

The knowledge of science from his previous life helped him in his magical journey as he sets to revolutionize magical tools. He is also capable of performing magical spells without words. Soon in this story, he almost breaks all the past scales of power level becoming almost the strongest.

5. The Rising of The Shield Hero

Naofumi Iwatani from The Rising Of The Shield Hero
  • AUTHOR: Aneko Yusagi
  • EPISODES: 25

If you love dark plots with overpowered Heroes you might like this. The circumstances for the protagonist from the beginning were hard. After being betrayed by everyone from a nation he decides to get stronger for sweet revenge. Do you think spears, swords, or bows are strong weapons? Your belief might get destroyed in this series as our MC is an OP shield user.

MAIN CHARACTER: Iwatani Naofumi 

I’ve gained more important things thanks to becoming the shield hero. Wherever the waves go I’ll go with my friends.

– Naofumi Iwatani


 Iwatani Naofumi, an easy-going Japanese student gets teleported to a parallel world along with 3 cardinal heroes. After being teleported to the other world he was betrayed by his party member and was also exiled out of the kingdom.

In the new world unbeknownst to the dangers, Naofumi loses all hope from his life. But soon after he forms a party with a demi-human Raphtalia and starts his journey. After forming his own party with Filo and Raphtalis he gets a reason to get stronger. He decides to protect them and save the world from any possible danger.

4. Mushoku Tensei: Jobless Reincarnation

Mushoku Tensei: Jobless Reincarnation
  • AUTHOR: Rifujin no Magonote
  • EPISODES: 23

A series that shows the life of a sad and hopeless person getting another chance at his pitiful life. This anime’s most eye-catching point is its world-building which the author has done very realistically. But throughout the series we see the main character getting stronger as he faces different difficult situations. As we travel through this world we came to know the power scaling which is significantly different than other Isekai. If you like a slow build-up plot for power-up you will love it.

MAIN CHARACTER: Rudeus Greyrat

“It’s no good to overestimate me. Victory is something that you grasp by always being modest, you know.”

– Rudeus Greyrat

An unnamed 34-year-old NEET who dies in a car accident wakes up in another world as a baby. He remembers everything from his past life even the traumas he went through. From birth, Rudeus is overpowered as he has the mental capacity of a 34-year-old man.

As time passes he started training under his father and a magician Roxy. Eventually, he gets better at both but as a magician, he reaches already a different level than others even crossing his teacher. Follow Rudeus and see how he protects the people he loves with his powers.

3. Soul Land(Douluo Dalu)

Tang San from Soul Land
  • AUTHOR: Tand Jia San Shao
  • EPISODES: 191 (Ongoing)

A Chinese anime series that comes in 3rd place on our list. Soul Land is an awesome series with beautiful world development and an awesome plotline. Our main character, who becomes overpowered as the story progresses, also takes part in some heart-wrenching fight sequences. This series is truly an underrated series when it comes to Isekai. If you haven’t watched it you must watch it soon. 


“Because you’re my father. My life was given by you. Without you, how would there be me? Children never have the right to blame their parents.”

– Tang San

Tang San, the most brilliant student of the Tang Sect, is a prodigy when it comes to martial arts and hidden weapons. But because of some incidents, he commits suicide and re-opens his eyes to the beautiful world of Soul Land. In this world, he learns soul power is everything. But he was born with the weakest combat spirit.

However, this doesn’t stop our protagonist in any way, as he begins his journey to be the greatest spiritual master of events. As he also remembered his memories he quickly jumps levels and becomes very strong. As the story hasn’t ended yet he is still getting stronger. But when it comes to the ability he is one in a million and also can defeat many opponents above his level.

Soul land is available on Youtube for free

2. Overlord

 Momonga from Overlord
  • AUTHOR: Kugane Maruyama
  • EPISODES: 39

What will the strongest character of a game do if he gets transported into the game itself? This anime focuses on the feelings of a being with unlimited powers. If you are a fan of a protagonist who has a dark side to himself and kills ruthlessly this series might be your cup of tea. The series is making a comeback with a movie and its 4th season this year.

MAIN CHARACTER: Ainz Ooal Gown(Momonga)

“Death by the sword. Death by broken bones. Death by crushing. There’s not much difference, right? You die at the end.”

– Ainz Ooal Gown

Ainz is the main protagonist and the leader of the guild Ainz Ooal Gown. He is also the Overlord of the Great Tomb of Nazarick and also the creator of Pandora’s Actor. The strongest of the 41 supreme beings of the game, Ainz-Sama has now teleported to E-Rantel, a city that looks like the game he used to play. The strong, mighty, and ruthless Ainz also has a soft side for the guardians and NPCs of Nazarick. 

Read More:
Best Isekai of All Time that You must Watch

1. That Time I Got Reincarnated as a Slime

Rimuru Tempest from That Time I Got Reincarnated as a Slime
  • AUTHOR: Fuse
  • EPISODES: 48 + 5 OVAs

A power fantasy series carrying one of the most overpowered main characters of Isekai. The most popular anime protagonist of 2019(by Crunchyroll), Rimuru is the strongest character on our list. But the surprise is that not only our MC is OP but also he created some monsters which are stronger than any normal OP MC.  If you still haven’t watched this series, watch it quickly or you will miss our little slime’s rampage on another world. 

MAIN CHARACTER: Rimuru Tempest

“To everyone who went against us, we will bare our fangs and retaliate. To everyone who lends their hands to us, we will grant our blessing to them. To our opponents, we will do to them what they have done to us. In the future, I hope that we can be linked in a friendship one day.” 

– Rimuru Tempest

Mikami Satoru after being stabbed to death gets reincarnated into another world as a Slime. In this new world, he meets the storm dragon Veldora and befriends him. He receives a name from him which is Rimuru Tempest. He has a unique ability called Predator. Predator gives Rimuru the power of the entities that he eats. He also later in the series becomes a Demon Lord. If you are an Isekai fan and like awesome action, this might be your perfect anime to watch.


Isekai Anime With An Overpowered Main Character

Now with that, we have come to the end of our list of the top 10 Isekai Anime with overpowered main characters!

Have you watched all of these anime? If you haven’t what are you waiting for? Comment below if you like our content and tell us which one is your favorite OP MC from our list.

Thanks a ton for reading thus far!

See ya!

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Subhrajit is a university student who loves to watch anime and read manga. He has been watching anime for a long time. Now he has decided to write and share his love for anime with others.
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